Chemical Structure : FEN1-IN-C20
CAS No.:
824983-94-0
FEN1-IN-C20
Catalog No. : PC-61813Not For Human Use, Lab Use Only.
FEN1-IN-C20 is an N‐hydroxyl urea derivative that specifically inhibits flap endonuclease 1 (FEN1) activity with IC50 of 3 nM.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6181301
Biological Activity
FEN1-IN-C20 is an N‐hydroxyl urea derivative that specifically inhibits flap endonuclease 1 (FEN1) activity with IC50 of 3 nM。
Physicochemical Properties
M.Wt
393.417
Formula
C20H15N3O4S
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
3'-((3-hydroxy-2,4-dioxo-3,4-dihydrothieno[3,2-d]pyrimidin-1(2H)-yl)methyl)-[1,1'-biphenyl]-4-carboxamide
References
1. Exell JC, et al. Nat Chem Biol.
2. He L, et al. Mol Oncol.
3. He L, et al. EBioMedicine.
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