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Chemical Structure : Cyclocreatine Phosphate
CAS No.: 18838-38-5
Catalog No.: PC-61918Not For Human Use, Lab Use Only.
Cyclocreatine Phosphate (AM 285) is an analog of the creatine kinase CKMT1 substrate creatine and inhibitor of the creatine biosynthesis pathway.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 100 mg | $58 | In stock | |
| 250 mg | $98 | In stock | |
| 1 g | Get quote |
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Cyclocreatine Phosphate (AM 285) is an analog of the creatine kinase CKMT1 substrate creatine and inhibitor of the creatine biosynthesis pathway.
Cyclocreatine Phosphate (AM 285) decreases intracellular ATP level, suppresses arginine-creatine metabolism, selectively decreases the viability, promotes cell cycle arrest and apoptosis of human EVI1-positive AML cells.
Cyclocreatine Phosphate (AM 285) prolongs survival in human orthotopic and mouse primary AML models.
| M.Wt | 287.3 | |
| Formula | C4H8N3O5P • 2K | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
N-[imino(phosphonoamino)methyl]-N-methyl-glycine, dipotassium salt |
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1. Woznicki DT, et al. J Neurochem. 1988 May;50(5):1640-7.
2. Turner DM, et al. J Biol Chem. 1987 May 15;262(14):6605-9.
3. Griffiths GR, et al. J Biol Chem. 1976 Apr 10;251(7):2049-54.
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