| Cat. No. |
Product Name |
Information |
| PC-60419 |
STL127705
Ku70/80 inhibitor
|
STL127705 (Ku70/80 inhibitor) is a novel small molecule inhibitor of the DNA repair protein Ku70/80, disrupts of Ku70/80-DNA interaction with IC50 of 3.5 uM in EMSA assay. |
| PC-60393 |
PBD-150
Glutaminyl cyclase inhibitor
|
PBD150 is a potent glutaminyl cyclase (QC) inhibitor with Ki of 60 nM. |
| PC-60357 |
MPO-IN-28
MPO inhibitor
|
MPO-IN-28 is a potent, irreversible Myeloperoxidase (MPO) inhibitor with IC50 of 44 nM. |
| PC-70176 |
MDL72527
Polyamine oxidase inhibitor
|
MDL72527 is a polyamine oxidase (PAO) inhibitor that inhibits spermine oxidase and N1-acetylpolyamine oxidase with IC50 of 6.1 and 0.02 uM, respectively. |
| PC-70160 |
5S rRNA modificator 2
RNA Probe
|
5S rRNA modificator 2 (NAI) is a novel chemical probe that enable selective 2’-hydroxyl acylation for accurate RNA structural analysis in living cells. |
| PC-70126 |
FPH2
iPSC-Heps inducer
|
FPH2 (BRD-9424) is a small molecule that promotes differentiation of iPS-derived hepatocytes, induces functional proliferation of hepatocytes in vitro, and thus expands mature human primary hepatocytes. |
| PC-70112 |
ATR-101
ACAT-1 inhibitor
|
ATR-101 (PD-132301, Nevanimibe) is a selective and potent inhibitor of ACAT1 with IC50 of 52 nM. |
| PC-60223 |
PF-DcpSi
DcpS inhibitor
|
PF-DcpSi is a potent inhibitor of the mRNA decapping scavenger enzyme (DcpS) with IC50 of 0.11 nM. |
| PC-60222 |
CK-2127107
Fast skeletal troponin activator
|
CK-2127107 (CK-107, Reldesemtiv) is a novel orally active fast skeletal troponin activator, selectively activates fast skeletal myofibrils with EC50 of 3.4 uM. |
| PC-60193 |
2-D08
UBC9 SUMOylation inhibitor
|
2-D08 is a cell permeable, mechanistically unique inhibitor of protein sumoylation, inhibits transcriptional expressions of SUMO1/2 and Ubc9. |
| PC-60184 |
Shield-1
FKBP ligand
|
Shield-1 is a cell-permeable FKBP ligand that is designed to protect an otherwise unstable protein domain from degradation. |
| PC-60177 |
CP-312
HO-1 inducer
|
CP-312 (Cardioprotectant 312) is a small molecule inducer of heme oxygenase-1 (HO-1) that protect human iPSC-derived cardiomyocytes from oxidative stress. |
