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DFPM

Chemical Structure : DFPM

CAS No.: 301338-95-4

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DFPM

Catalog No.: PC-61225Not For Human Use, Lab Use Only.

DFPM is a small molecule that rapidly downregulates abscisic acid (ABA)-dependent gene expression (IC50=3 and 1.5 uM for RD29B and RAB18 promoters), also inhibits ABA-induced stomatal closure.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    DFPM is a small molecule that rapidly downregulates abscisic acid (ABA)-dependent gene expression (IC50=3 and 1.5 uM for RD29B and RAB18 promoters), also inhibits ABA-induced stomatal closure.
    DFPM stimulates expression of plant defense-related genes, major early regulators of pathogen-resistance responses, including EDS1, PAD4, RAR1, and SGT1b, are required for DFPM-interference with ABA signal transduction, disrupts cytosolic Ca(2+) signaling and downstream anion channel activation in a PAD4-dependent manner.

    Physicochemical Properties

    M.Wt 340.262
    Formula C16H15Cl2NOS
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    [5-(3,4-dichlorophenyl)furan-2-yl]-piperidine-1-ylmethanethione

    References

    1. Kim TH, et al. Curr Biol. 2011 Jun 7;21(11):990-7.

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