Catalog No.: PC-61236Not For Human Use, Lab Use Only.
AGI-1067 (Succinobucol) is a potent inhibitor of TNF-α-inducible expression of VCAM-1, MCP-1 and E-selectin (IC50=6,10 and 25 uM) with concurrent antioxidant and lipid-modulating properties.
AGI-1067 (Succinobucol) is a potent inhibitor of TNF-α-inducible expression of VCAM-1, MCP-1 and E-selectin (IC50=6,10 and 25 uM) with concurrent antioxidant and lipid-modulating properties.
AGI-1067 (Succinobucol) inhibits atherosclerosis in LDL receptor-deficient and apolipoprotein E-deficient mice.
AGI-1067 (Succinobucol) also reduces VCAM-1 and MCP-1 mRNA levels in lungs of LPS-stimulated mice.
AGI-1067 (Succinobucol) inhibits atherosclerosis not only via its lipid-lowering effects but also by having direct anti-inflammatory effects on the vessel wall.
