Catalog No.: PC-70267Not For Human Use, Lab Use Only.
Shz-3 is a small cardiogenic molecule that potently induces Nkx2.5 and a subset of other cardiac markers, including myocardin, troponin-I, and sarcomeric α-tropomyosin (SαTM) in a variety of different stem/progenitor cells.
Shz-3 is a small cardiogenic molecule that potently induces Nkx2.5 and a subset of other cardiac markers, including myocardin, troponin-I, and sarcomeric α-tropomyosin (SαTM) in a variety of different stem/progenitor cells.
Shz-3 triggers cardiac mRNA and protein expression in a variety of embryonic and adult stem/progenitor cells, including human mobilized peripheral blood mononuclear cells (M-PBMCs).
Shz-3 displays cardioregenerative activity as xenografts in injured immunocompromised rat heart.
