| Cat. No. |
Product Name |
Information |
| PC-26237 |
HF13141-H5
GGCX inhibitor
|
HF13141-H5 is a potent, selective inhibitor of γ-Glutamyl carboxylase (GGCX) with IC50 of 240 nM-1 uM in cell-based assays, inhibits γ-carboxylation of vitamin K-dependent clotting factors (VKDCFs) and shows anticoagulant effect. |
| PC-26220 |
Thiostrepton
FOXM1 inhibitor, PRX3 inhibitor
|
Thiostrepton is a thiazole antibiotic that selectively inhibits FOXM1, also significantly inhibits ETV4 K97-Khib, thereby promoting ferroptosis and suppressing ICC cell migration, invasion, and lung metastasis, covalently inhibits Peroxiredoxin 3 (PRX3), disrupting redox balance and selectively induces tumor cell death. |
| PC-26205 |
CN-0928
PCBP2 inhibitor
|
CN-0928 is a specific small molecule inhibitor of poly(C)-binding protein 2 (PCBP2), mitigates AD pathology by inhibiting PCBP2 condensation. |
| PC-26181 |
CAPib-13
CAP-1 inhibitor
|
CAPib-13 is a small-molecule inhibitor of CAP-1 (cyclase-associated protein-1) with SPR KD of 2.57 uM, significantly suppresses colorectal cancer metastasis. |
| PC-26148 |
NFAT Inhibitor VIVIT peptide
NFAT inhibitor
|
NFAT Inhibitor VIVIT peptide is a peptide inhibitor of nuclear factor of activated Tcells (NFAT), selectively inhibits calcineurin-mediated dephosphorylation of NFAT. |
| PC-26147 |
A-285222
NFAT inhibitor
|
A-285222 (A-285) is a bis-trifluoromethyl-pyrazole (BTP) and selective nuclear factor of activated T cells (NFAT) inhibitor, inhibits PBMC proliferation stimulated by concanavalin A with IC50 of 146 nM, inhibits IL-2 synthesis in human blood with IC50 of 182 nM. |
| PC-26146 |
INCA-6
NFAT inhibitor
|
INCA-6 (Inhibitor of NFAT-calcineurin association 6) is a specific, cell-permeable nuclear factor of activated T cells (NFAT) inhibitor, binds to calcineurin with high affinity (KD=0.8 uM) and specifically disrupts its interaction with NFAT. |
| PC-26112 |
GSK902056A
PKN3 inhibitor
|
GSK902056A is a highly potent inhibitor of serine/threonine kinase PKN3 with Kdapp of 1 nM, potently engaged PKN3 in cells with IC50 of 79 nM. |
| PC-26109 |
SOD1 lactylation inhibitor ZL-01
SOD1K123la inhibitor
|
SOD1 lactylation inhibitor ZL-01 is a potential specifi inhibitor of csuperoxide dismutase 1 (SOD1) lactylation at lysine 123 (SOD1K123la), effectively reduces the SOD1K123la level and increases SOD1 activity. |
| PC-26108 |
Py-Pip
Neurolysin activator
|
Py-Pip is a nonpeptide small molecule activator of Neurolysin (Nln), enhances the activity of peptidase neurolysin. |
| PC-26087 |
MKV3
Cu+-ATPases inhibitor
|
MKV3 is a specific, first-in-class, broad spectrum inhibitor of Cu-transporting P-type ATPases targeting P1B-type copper ATPases, binds within the Cu+ entry pocket, thereby blocking Cu+ delivery to the intramembranous transport site, dependently decreases Cu+-stimulated ATPase activity with IC50 of 130 nM for Escherichia coli Cu+-ATPase CopA (EcCopA). |
| PC-26076 |
ERX-208
LIPA inhibitor, ERS inducer
|
ERX-208 is a small molecule ERX-41 analog that binds stereospecifically to lysosomal acid lipase A (LIPA), induces endoplasmic reticulum stress (ERS) and apoptosis in a panel of OCa cell lines in vitro (IC50=100 nM). |
