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PIP5K inhibitor 20

Chemical Structure : PIP5K inhibitor 20

CAS No.: 2888538-18-7

PIP5K inhibitor 20 (PIP5K inhibitor)

Catalog No.: PC-20371Not For Human Use, Lab Use Only.

PIP5K inhibitor 20 is a potent, selective pan-PIP5K inhibitor with IC50 values of 58, 46 and 39 nM for PIP5Kα, PIP5Kβ and PIP5Kγ, respectively.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    PIP5K inhibitor 20 is a potent, selective pan-PIP5K inhibitor with IC50 values of 58, 46 and 39 nM for PIP5Kα, PIP5Kβ and PIP5Kγ, respectively.

    Physicochemical Properties

    M.Wt 472.55
    Formula C27H28N4O4
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-((1,3-dioxolan-2-yl)methyl)-3-(2-(cyclopropanecarboxamido)pyridin-4-yl)-N-methyl-5-(phenylamino)benzamide

    References

    1. Andrews DM, et al. Bioorg Med Chem. 2022 Jan 15;54:116557.

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