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SYNTi

Chemical Structure : SYNTi

CAS No.:

SYNTi

Catalog No.: PC-20346Not For Human Use, Lab Use Only.

SYNTi is a small molecule PDZ domain inhibitor targeting the syndecan/syntenin protein-protein interaction with IC50 of 400 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    SYNTi is a small molecule PDZ domain inhibitor targeting the syndecan/syntenin protein-protein interaction with IC50 of 400 nM.

    Physicochemical Properties

    M.Wt 567.41
    Formula C28H24BrFN2O5
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    ((S)-3-(5'-acetyl-2'-fluoro-[1,1'-biphenyl]-4-yl)-2-(6-bromo-3-oxoindolin-1-yl)propanoyl)-L-alanine

    References

    1. Laurent Hoffer, et al. J Med Chem. 2023 Mar 20. doi: 10.1021/acs.jmedchem.2c01569.

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