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Chemical Structure : HTL0041178
Catalog No.: PC-20325Not For Human Use, Lab Use Only.
HTL0041178 is a potent GPR52 agonist with EC50 of 27.5 nM (human or rat GPR52).
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HTL0041178 is a potent GPR52 agonist with EC50 of 27.5 nM (human or rat GPR52).
HTL0041178 exhibits a promising pharmacokinetic (PK) profile, and oral activity in rodent preclinical models.
HTL0041178 (10 mg/kg, p.o.) caused a dose-related reduction in d-amphetamine-stimulated hyperlocomotion in rats.
| M.Wt | 390.34 | |
| Formula | C19H14F4N4O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Patent WO2021090030
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