| Cat. No. |
Product Name |
Information |
| PC-62311 |
PF-9366
MAT2A inhibitor
|
PF-9366 is a novel selective, allosteric methionine adenosyltransferase 2A (Mat2A) inhibitor with IC50 of 420 nM, Kd of 170 nM. |
| PC-62300 |
FEN1-IN-1
FEN1 inhibitor
|
FEN1-IN-1 is a potent, selective Flap Endonuclease-1 (FEN1) inhibitor with IC50 of 11 nM. |
| PC-62296 |
Miquelianin
|
Miquelianin (Quercetin-3-O-glucuronide) is a flavonol glucuronide that shows an antioxidant effect in human plasma. |
| PC-62259 |
Inflachromene
|
Inflachromene (ICM) is a microglial inhibitor with anti-inflammatory effects, directly binds high mobility group protein 1 (HMGB1) and HMGB2 and reduces their cytoplasmic accumulation in microglial cells. |
| PC-62252 |
WWL229
Ces3 inhibitor
|
WWL229 is a selective, distinct Carboxylesterase Ces3 inhibitor with IC50 of 1.94 uM, but not Ces1f, ABHD6, other serine hydrolases. |
| PC-62245 |
Triphenyl compound A
Pirin inhibitor
|
Triphenyl compound A (TPh A) is a small-molecule inhibitor of nuclear protein Pirin with Kd of 0.6 uM, inhibits the interaction between pirin and Bcl3 in vitro and in cells. |
| PC-62234 |
Golgicide A
ArfGEF GBF1 inhibitor
|
Golgicide A is a potent, highly specific, reversible inhibitor of the cis-Golgi ArfGEF GBF1, inhibits the effect of shiga toxin on protein synthesis with IC50 of 3.3 uM. |
| PC-62221 |
ML239
|
ML239 is a selective small molecule inhibitor of breast cancer stem cells with IC50 of 1.18 uM, displays >23-fold selective inhibition of the breast CSC-like cell line over the isogenic control cell line. |
| PC-62204 |
AA 41612
OPN4 antagonist
|
AA 41612 is a potent, synthetic melanopsin antagonist with IC50 of 15.8 nM, attenuates melanopsin photocurrent in a dose-dependent manner. |
| PC-62152 |
GGTI 2418
GGTase I inhibitor
|
GGTI 2418 (GGTI-2418, PTX 100) is a highly potent, competitive, and selective peptidomimetic inhibitor of geranylgeranyltransferase I (GGTI) with IC50 of 9.5 nM, displays 5,600-fold selectivity over FTase. |
| PC-62151 |
GGTI-2417
GGTase I inhibitor
|
GGTI-2417 is the methyl ester prodrug of GGTI-2418, a highly potent, competitive, and selective inhibitor of GGTase I. |
| PC-62122 |
ML382
MRGPRX1 modulator
|
ML382 is a potent, selective, positive allosteric modulator of Mas-related G protein-coupled receptor X1 (MrgprX1) with EC50 of 190 nM in cell based Ca2+ imaging assay. |
