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Chemical Structure : FECH inhibitor 4e
Catalog No.: PC-72887Not For Human Use, Lab Use Only.
FECH inhibitor 4e (FECH-IN-4e) is a potent, specifc, competitive inhibitor of ferrochelatase (FECH) with IC50 in the high-nanomolar range.
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FECH inhibitor 4e (FECH-IN-4e) is a potent, specifc, competitive inhibitor of ferrochelatase (FECH) with IC50 in the high-nanomolar range.
FECH inhibitor 4e inhibited HREC migration in a dose-dependent manner, without cytotoxic effects.
FECH inhibitor 4e caused statistically significant PPIX accumulation, showed HREC antiproliferative activity.
Intravitreal injections of FECH inhibitor 4e decreased neovascularization in vivo.
| M.Wt | 424.508 | |
| Formula | C25H24N6O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Kamakshi Sishtla, et al. Cell Chem Biol. 2022 Jan 25;S2451-9456(22)00001-0.
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