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ABA Antagonist AA1

Chemical Structure : ABA Antagonist AA1

CAS No.: 450346-85-7

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ABA Antagonist AA1

Catalog No.: PC-72915Not For Human Use, Lab Use Only.

ABA Antagonist AA1 is a small molecule that inhibits ABA signaling with IC50 of 2.5 uM, targets all ABA receptors.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    ABA Antagonist AA1 is a small molecule that inhibits ABA signaling with IC50 of 2.5 uM, targets all ABA receptors.
    AA1 inhibits ABA-responsive gene expression.
    AA1 interferes with all the interactions between PYR/PYL and PP2C to release PP2C activity, YR/PYLs are direct targets of AA1.
    Abscisic acid (ABA), the most important stress-induced phytohormone, regulates seed dormancy, germination, plant senescence, and the abiotic stress response.

    Physicochemical Properties

    M.Wt 389.536
    Formula C18H23N5OS2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    3-((4-benzylpiperazin-1-yl)methyl)-2-thioxo-2,3,6,7-tetrahydro-[1,3,4]thiadiazolo[3,2-a][1,3]diazepin-8(5H)-one

    References

    1. Yajin Ye, et al. Plant Physiol. 2017 Apr;173(4):2356-2369.

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