| Cat. No. |
Product Name |
Information |
| PC-61795 |
Cromoglicic acid
Mast cell stabilizer
|
Cromoglicic acid (Cromolyn, FPL-670) is a mast cell stabilizer with anti-inflammatory activity that prevents the release of inflammatory chemicals such as histamine, leukotrienes from mast cells. |
| PC-61794 |
Sodium cromoglicate
Mast cell stabilizer
|
Sodium cromoglicate is a mast cell stabilizer with anti-inflammatory activity that prevents the release of inflammatory chemicals such as histamine, leukotrienes from mast cells. |
| PC-61784 |
NSC 15765
DNA2 nuclease inhibitor
|
NSC 15765 (Compound C5, DNA2 inhibitor C5) is an effective, selective and competitive inhibitor of DNA2 nuclease with IC50 of 20 uM. |
| PC-61782 |
J147
Neuroprotective agent
|
J 147 is a potent, orally active, memory enhancing and neurotrophic agent that protects against neurotoxicity in cortical neurons in vitro with EC50 of 25-200 nM. |
| PC-61781 |
CAD-031
Neuroprotective agent
|
CAD-031 (CAD31) is a novel brain penetrant, J147-derivative that has enhanced neurogenic activity over J147 in human neural precursor cells (NPCs). |
| PC-61734 |
R-283
hTG2 inhibitor
|
R-283 is a potent and selective human tissue transglutaminase (hTG2) inhibitor with IC50 of 4 uM.. |
| PC-61730 |
FPPS inhibitor OX14
FPPS inhibitor
|
OX14 is a highly potent farnesyl pyrophosphate synthase (FPPS) inhibitor with IC50 of 2.46 nM, with significantly lower binding affinity to hydroxyapatite. |
| PC-61689 |
Fhit-IN-15
Fhit inhibitor
|
Fhit-IN-15 is a potent, competitive, reversible inhibitor of the enzymatic activity of tumor suppressor Fhit with IC50 of 49 nM, shows cytotoxicity in HEK293T cells. |
| PC-61683 |
Juglone
|
Juglone (5-HN) is a plant-derived 1,4-naphthoquinone with confirmed antibacterial and antitumor activities. |
| PC-61677 |
ATN-224
SOD1 inhibitor
|
ATN-224 (Choline tetrathiomolybdate, WTX-101) is a specific, high-affinity copper binder that inhibits CuZn superoxide dismutase 1 (SOD1) with IC50 of 0.33 uM against purified bovine SOD1, leading to antiangiogenic and antitumour effects. |
| PC-61674 |
SBI-993
MondoA inhibitor
|
SBI-993 is an analog of SBI-477 that shows improved potency and suitable pharmacokinetic properties for in vivo bioavailability. |
| PC-61673 |
SBI-477
MondoA inhibitor
|
SBI-477 is a chemical probe that coordinately inhibits triacylglyceride (TAG) synthesis and enhances basal glucose uptake in human skeletal myocytes with EC50 of 100 nM and 1 uM, respectively. |
