| Cat. No. |
Product Name |
Information |
| PC-62151 |
GGTI-2417
GGTase I inhibitor
|
GGTI-2417 is the methyl ester prodrug of GGTI-2418, a highly potent, competitive, and selective inhibitor of GGTase I. |
| PC-62124 |
ML387
HPGD inhibitor
|
ML387 (CID3474778) is a potent, selective NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (HPGD) inhibitor with IC50 of 19 nM. |
| PC-62123 |
ML388
HPGD inhibitor
|
ML388 is a potent, selective NAD+-dependent 15-hydroxyprostaglandin dehydrogenase (HPGD) inhibitor with IC50 of 34 nM. |
| PC-62122 |
ML382
MRGPRX1 modulator
|
ML382 is a potent, selective, positive allosteric modulator of Mas-related G protein-coupled receptor X1 (MrgprX1) with EC50 of 190 nM in cell based Ca2+ imaging assay. |
| PC-62119 |
ML377
TAG accumulation inhibitor
|
ML377 (MLS-0472732) is a small molecule probe that selectively inhibits TAG (Triacylglyceride) accumulation with an IC50 of 1.1 uM, show >45-fold selectivity versus DGAT inhibition and cytotoxicity. |
| PC-62075 |
Gerfelin
Glyoxalase I inhibitor
|
Gerfelin is an osteoclastogenesis inhibitor (IC50=61 uM) through the competitive inhibition of glyoxalase I (GLO1) with Ki of 0.15 uM. |
| PC-62074 |
Methyl Gerfelin
Glyoxalase I inhibitor
|
Methyl Gerfelin (M-GFN) is an osteoclastogenesis inhibitor (IC50=2.8 uM) through the competitive inhibition of glyoxalase I (GLO1) with Ki of 0.23 uM. |
| PC-62073 |
Surfen hydrate
Heparan sulfate antagonist
|
Surfen hydrate is a small molecule antagonist of heparan sulfate, binds to heparin, low molecular weight heparins, and to HS and other GAGs. |
| PC-62072 |
Surfen
Heparan sulfate antagonist
|
Surfen is a small molecule antagonist of heparan sulfate, binds to heparin, low molecular weight heparins, and to HS and other GAGs. |
| PC-62062 |
CMA-008
NAADP inhibitor
|
CMA-008 is a cell-permeable, small molecule modulator of NAADP-mediated Ca2+ release, competes with NAADP binding, inhibits Ca2+ release via the NAADP receptor (IC50=15 uM-1 mM). |
| PC-62061 |
BZ194
NAADP inhibitor
|
BZ194 (BZ-194) is a small molecule inhibitor of NAADP action that inhibit NAADP-mediated Ca2+ signaling in T cells, neither interferes with Ca2+ mobilization by IP3 or cyclic ADP-ribose nor with capacitative Ca2+ entry. |
| PC-62059 |
FSC231
PICK1 inhibitor
|
FSC231 (FSC-231) is the first, cell-permeable small-molecule inhibitor of PICK1 PDZ domain with Kd of 10.1 uM. |
