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Chemical Structure : BCI-137
Catalog No.: PC-62379Not For Human Use, Lab Use Only.
BCI-137 is a chemical compound able to compete with Argonaute 2 miRNAs binding, binds to Ago2 with Kd of 126 uM.
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BCI-137 is a chemical compound able to compete with Argonaute 2 miRNAs binding, binds to Ago2 with Kd of 126 uM.
BCI-137 displaces Ago2 from the miR-155 host gene promoter paralleling an increase in histone H4 acetylation, favors RA-induced differentiation of the APL cell line NB4.
| M.Wt | 313.284 | |
| Formula | C11H11N3O6S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Masciarelli S, et al. ACS Chem Biol. 2014 Aug 15;9(8):1674-9.
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