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Chemical Structure : OSMI-1
CAS No.: 1681056-61-0
Catalog No.: PC-62387Not For Human Use, Lab Use Only.
OSMI-1 is a cell-permeable, small molecule O-GlcNAc transferase (OGT) inhibitor with IC50 of 2.7 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $128 | In stock | |
| 25 mg | $228 | In stock | |
| 50 mg | $388 | In stock | |
| 100 mg | Get quote |
Bulk size, bulk discount!
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OSMI-1 is a cell-permeable, small molecule O-GlcNAc transferase (OGT) inhibitor with IC50 of 2.7 uM.
OSMI-1 inhibits protein O-GlcNAcylation in several mammalian cell lines without qualitatively altering cell surface N- or O-linked glycans.
OSMI-1 also significantly decreases HSV replication.
| M.Wt | 563.64 | |
| Formula | C28H25N3O6S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
αR-[[(1,2-dihydro-2-oxo-6-quinolinyl)sulfonyl]amino]-N-(2-furanylmethyl)-2-methoxy-N-(2-thienylmethyl)-benzeneacetamide |
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1. Ortiz-Meoz RF, et al. ACS Chem Biol. 2015 Jun 19;10(6):1392-7.
2. Angelova M, et al. J Virol. 2015 Aug;89(16):8474-83.
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