RH01687 |CAS:302901-13-9 Probechem Biochemicals

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Chemical Structure : RH01687

CAS No.: 302901-13-9

RH01687 (RH 01687)

Catalog No.: PC-62382Not For Human Use, Lab Use Only.

RH01687 is a small molecule that protect pancreatic β cells against endoplasmic reticulum stress-induced cell death.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

RH01687 is a small molecule that protect pancreatic β cells against endoplasmic reticulum stress-induced cell death.
RH01687 increases the survival of human primary β cells and rodent β cell lines subjected to ER stressors including palmitate>
RH01687 also restores ER stress-impaired glucose-stimulated insulin secretion responses.

Physicochemical Properties

M.Wt	336.754
Formula	C12H9ClN6O2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(4-Chloro-2-nitro-5-pyrrol-1-ylphenyl)sulfanyl-1H-1,2,4-triazol-5-amine

References

1. Tran K, et al. ACS Chem Biol. 2014 Dec 19;9(12):2796-806.

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RH01687 (RH 01687)

Biological Activity

Physicochemical Properties

References

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