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AGPS inhibitor 1a

Chemical Structure : AGPS inhibitor 1a

CAS No.: 1807978-35-3

AGPS inhibitor 1a (AGPS-IN-1a)

Catalog No.: PC-62394Not For Human Use, Lab Use Only.

AGPS inhibitor 1a (AGPS-IN-1a) is a potent inhibitor of the ether lipid-generating enzyme alkyl-glycerone phosphate synthase (AGPS), selectively lowers ether lipid levels in several types of human cancer cells and impairs their cellular survival and migration.

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    Biological Activity

    AGPS inhibitor 1a (AGPS-IN-1a) is a potent inhibitor of the ether lipid-generating enzyme alkyl-glycerone phosphate synthase (AGPS), selectively lowers ether lipid levels in several types of human cancer cells and impairs their cellular survival and migration.

    Physicochemical Properties

    M.Wt 327.359
    Formula C18H18FN3O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    3-(2-fluorophenyl)-N-((2-oxo-2,3-dihydro-1H-benzo[d]imidazol-5 yl)methyl)butanamide

    References

    1. Piano V, et al. ACS Chem Biol. 2015 Nov 20;10(11):2589-97.

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