Cat. No. |
Product Name |
Information |
PC-72067 |
ALC-0159
PEGylated lipid
|
ALC-0159 is a PEGylated lipid which has been used to form lipid nanoparticles for delivery of RNA. ALC-0159 is one of the components in the BNT162b2 vaccine against SARS-CoV-2 in addition to ALC-0315, DSPC, and cholesterol. |
PC-72028 |
NIO-1
OCT1 inhibitor
|
NIO-1 (Novel inhibitor of OCT1) is a novel small molecule inhibitor of Octamer transcription factor OCT1, inhibits OCT1 activation with IC50 of 0.11 uM. |
PC-72026 |
AZ13792138
NUDT1 inhibitor
|
AZ13792138 is a highly potent, selective inhibitor of MTH1 (NUDT1) with Kd/IC50 of 0.4/0.5 nM. |
PC-72024 |
SU0268
OGG1 inhibitor
|
SU0268 (SU 0268) is a potent, selective, noncovalent inhibitor DNA repair enzyme 8-oxoguanine DNA glycosylase (OGG1) with IC50 of 59 nM. |
PC-72022 |
BIM5078
HNF4α antagonist
|
BIM5078 (BIM-5078) is a potent synthetic HNF4α antagonist, binds to HNF4α with high affinity (EC50=11.9 nM) and modulates HNF4α target genes and metabolic processes controlled by HNF4α. |
PC-72021 |
BI6015
HNF4α antagonist
|
BI6015 (BI-6015) is a potent synthetic HNF4α antagonist, binds to HNF4α with high affinity and modulates HNF4α target genes and metabolic processes controlled by HNF4α. |
PC-72017 |
INI-60
Kpnβ1 inhibitor
|
INI-60 (Inhibitor of Nuclear Import-60) is a novel small molecule inhibitor of Kpnβ1-mediated nuclear import with anti-cancer activity. |
PC-72016 |
CNI103
Calcineurin-NFAT inhibitor
|
CNI103 (CNI-103) is a highly potent, cell-permeable, metabolically stable peptidyl inhibitor of Calcineurin-NFAT interaction wioth KD 16 nM and IC50 of 220 nM. |
PC-72005 |
Reproxalap
RASP inhibitor
|
Reproxalap (ADX-102) is a novel inhibitor of reactive aldehyde species (RASP) for the treatment of ocular inflammation. |
PC-38334 |
CARD8 activator CQ31
|
CARD8 activator CQ31 is a small molecule that selectively activates CARD8. |
PC-38326 |
DMT1inhibitor 18a
|
DMT1 inhibitor 18g is the most potent inhibitor of divalent metal transporter 1 (DMT1) with IC50 of 50 nM in calcein fluorescence assay.. |
PC-38325 |
DMT1 inhibitor 14a
|
DMT1 inhibitor 14a is a potent inhibitor of divalent metal transporter 1 (DMT1) with IC50 of 340 nM in calcein fluorescence assay. |