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Cat. No. Product Name Information
PC-22766

Pertussis Toxin

Gi protein inhibitor

Pertussis Toxin is a protein-based AB5-type exotoxin produced by the bacterium Bordetella pertussis, inhibits G protein-coupled receptor (GPR) signaling through Gi proteins.
PC-22760

AS1411

Nucleolin inhibitor

AS1411 is a quadruplex-forming oligonucleotide aptamer that targets nucleolin, inhibits cancer cell proliferation.
PC-22755

GCS-12

NKT cell agonist

GCS-12 is a highly potent αGalCer sulfonamide analogue as natural killer T (NKT) cell agonist, enhances interaction of the glycolipid/CD1d complex, exhibits selectivity for the induction of IFN-γ over IL-4, shows potent antitumor activities.
PC-22754

GCS-11

NKT cell agonist

GCS-11 is a highly potent αGalCer sulfonamide analogue as natural killer T (NKT) cell agonist, enhances interaction of the glycolipid/CD1d complex, exhibits selectivity for the induction of IFN-γ over IL-4, shows potent antitumor activities.
PC-22713

Bongkrekic acid

Mitochondrial toxin

Bongkrekic acid is a specific small molecule inhibitor of the adenine nucleotide translocase of mitochondria and mitochondrial toxin secreted by the bacteria Pseudomonas cocovenenans, inhibits ADP/ATP transport.
PC-22708

Necrox-7

HMGB1 inhibitor, Necrosis inhibitor

NecroX-7 (NecX, NecroX 7) is a small molecule necrosis inhibitor by inhibiting high-mobility group box 1 protein (HMGB1) release.
PC-22695

LH1753

L-cystine crystallization inhibitor

LH1753 is an orally bioavailable inhibitor of L-cystine crystallization for cystinuria, prevents stone formation effectively in the Slc3a1-knockout mouse model.
PC-22694

DS21360717

FER kinase inhibitor

DS21360717 is a highly potent inhibitor of feline sarcoma-related (FER) tyrosine kinase tyrosine kinase with IC50 of 0.49 nM, shows in vivo antitumor efficacy.
PC-22693

DS08701581

FER kinase inhibitor

DS08701581 is a highly potent inhibitor of feline sarcoma-related (FER) tyrosine kinase with IC50 of 0.32 nM, shows in vivo antitumor efficacy.
PC-22686

NSI-189 phosphate

Neurogenic compound

NSI-189 phosphate is an orally active benzylpiperizine-aminiopyridine compound with neurogenic activity, stimulates neurogenesis of human hippocampus-derived neural stem cells in vitro and stimulates neurogenesis in murine hippocampus in vivo.
PC-22685

NSI-189

Neurogenic compound

NSI-189 is an orally active benzylpiperizine-aminiopyridine compound with neurogenic activity, stimulates neurogenesis of human hippocampus-derived neural stem cells in vitro and stimulates neurogenesis in murine hippocampus in vivo.
PC-22683

FR900359

pan-Gq inhibitor

FR900359 is a plant-derived depsipeptide and specific pan-Gq (Gq/11/14) inhibitor, selectively inhibits Gq-dependent signalling, with little effect on Galphasbetagamma, Galphaibetagamma, or Galpha12/13betagamma heterotrimer activity.

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