| Cat. No. |
Product Name |
Information |
| PC-24086 |
MASP-2 inhibitor 77
MASP-2 inhibitor
|
MASP-2 inhibitor 77 is a potent, specific small-molecule inhibitor of mannan-binding lectin-associated serine proteases -2 (MASP-2) with IC50 of 11.2 nM, >100-fold selective over MASP-3. |
| PC-24075 |
Nickel(II) bromide
CAS 13462-88-9
|
Nickel bromide is a bromide of nickel. |
| PC-24063 |
RP-54745
IL-1 Inhibitor
|
RP-54745 is a potential antirheumatic compound and interleukin-1 (IL-1) inhibitor, inhibits LPS-induced IL-1 production by murine peritoneal macrophages. |
| PC-24062 |
Germinone
KAI2 agonist
|
Germinone (Germinone A) is a small molecule agonist HTL/KAI2 (KAI2), also binds to DWARF14 (D14), shows germination-inducing activity for thermo-inhibited Arabidopsis seed. |
| PC-24061 |
(+)-dMGer
KAI2 agonist
|
(+)-dMGer ((R)-dMGer) is a potent agonist of Karrikin Insensitive 2 (KAI2), inhibits KAI2 hydrolytic activity with IC50 of 0.16 uM. |
| PC-24060 |
dMGer
KAI2 agonist
|
dMGer (DesmethylGerminone) is a potent and selective HTL/KAI2 (KAI2) agonist, inhibits KAI2-dependent dMYLG hydrolysis with IC50 of 46 nM. |
| PC-24048 |
BM-8372
TLT-1 inhibitor
|
BM-8372 is a potential small molecule inhibitor of TREM-like transcript-1 (TLT-1), inhibits the binding to fibrinogen, demonstrates significant effect in platelet aggregation and spreading assays. |
| PC-24044 |
TIX100
TXNIP inhibitor
|
SRI-37330 (TIX100) is an orally available small molecule that regulates TXNIP expression, inhibits endogenous TXNIP mRNA expression (IC50=0.64 uM, INS-1 cells qRT-PCR assays). |
| PC-24039 |
RUN-47
NRF1 activator
|
RUN-47 is a small-molecule activator of NRF1 with EC50 of 6.43 uM in 3xPSMA4-ARE-LUC reporter assays, specifically activates NRF1 pathway. |
| PC-24030 |
Diacerein
IL-1β inhibitor
|
Diacerein (Diacerhein) is an orally active anthraquinone, reduces production of IL-1 converting enzyme then inhibits the activation of IL-1β by related downstream signaling, also is a highly efficacious inhibitor of main protease (Mpro) of SARS-CoV-2, shows anti-inflammatory and anti-rheumatic effect. |
| PC-24009 |
Apigenin
MARK4 inhibitor
|
Apigenin is a small molecule inhibitor of Microtubule Affinity-Regulating Kinase 4 (MARK4) with IC50 of 2.39 uM, exerts neuroprotective effects. |
| PC-24008 |
ST-5-002
TM4SF5 inhibitor
|
ST-5-002 is a specific small molecule inhibitor of transmembrane 4 L six family member 5 (TM4SF5), inhibits signaling lymphocytic activation molecule family member 7 (SLAMF7) degradation due to TM4SF5 binding and lysosomal translocation. |
