Pfn1-actin interaction inhibitor C1

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Chemical Structure : Pfn1-actin interaction inhibitor C1

Catalog No.: PC-25253Not For Human Use, Lab Use Only.

Pfn1-actin interaction inhibitor C2 is a specific small molecule inhibitor of profilin1 (Pfn1)-actin interaction, inhibits the angiogenic ability of vascular endothelial cells (ECs), affects the actin cytoskeleton, migration, and proliferation of ECs.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Pfn1-actin interaction inhibitor C1 is a specific small molecule inhibitor of profilin1 (Pfn1)-actin interaction, inhibits the angiogenic ability of vascular endothelial cells (ECs), affects the actin cytoskeleton, migration, and proliferation of ECs.

Physicochemical Properties

M.Wt	373.38
Formula	C19H15N7O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	8-(3-hydroxyphenyl)-10-(4-methylphenyl)-2,4,5,6,7,11,12-heptaazatricyclo[7.4.0.03,7]trideca-1(13),3,5,9,11-pentaen-13-ol

References

1. Gau D, et al. J Biol Chem. 2018 Feb 16;293(7):2606-2616.

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