Pfn1-actin interaction inhibitor C2

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Chemical Structure : Pfn1-actin interaction inhibitor C2

Catalog No.: PC-25254Not For Human Use, Lab Use Only.

Pfn1-actin interaction inhibitor C2 is a specific small molecule inhibitor of profilin1 (Pfn1)-actin interaction, inhibits the angiogenic ability of vascular endothelial cells (ECs), affects the actin cytoskeleton, migration, and proliferation of Ecs.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Physicochemical Properties

M.Wt	359.35
Formula	C18H13N7O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	8-(3-hydroxyphenyl)-10-phenyl-2,4,5,6,7,11,12-heptaazatricyclo[7.4.0.03,7]trideca-1(13),3,5,9,11-pentaen-13-ol

References

1. Gau D, et al. J Biol Chem. 2018 Feb 16;293(7):2606-2616.

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