| Cat. No. |
Product Name |
Information |
| PC-21325 |
MV-658
ENPP1 inhibitor
|
MV658 (ENPP1-IN-1) is a potent small molecule ENPP1 inhibitor (IC50= 11 nM) as immune modulator. |
| PC-21299 |
2-MPPA
GCP-II Inhibitor
|
2-MPPA (GPI-5693) is a potent, selective and orally active glutamate carboxypeptidase II (GCP II, NAALADase) inhibitor with IC50 of 90 nM. |
| PC-21294 |
NVS1.1
Readthrough promoter
|
NVS1.1 is a potent readthrough promoter, promotes the rapid and specific degradation of eukaryotic release factor 1 (eRF1) and restores functional full-length proteins in cystic fibrosis and Hurler disease models. |
| PC-21278 |
MSN-CD44 inhibitor 2
CD44-MSN inhibitor
|
MSN-CD44 inhibitor 2 is a small molecule FERM domain protein-protein interaction inhibitor for moesin (MSN) and CD44 with SPR KD of 0.7 uM, is a potent inhibitor of CD44-MSN interaction in live cells with IC50 of 200 nM. |
| PC-21277 |
MSN-CD44 inhibitor 1
CD44-MSN inhibitor
|
MSN-CD44 inhibitor 1 is a small molecule FERM domain protein-protein interaction inhibitor for moesin (MSN) and CD44 with SPR KD of 4.2 uM, is a potent inhibitor of CD44-MSN interaction in live cells with IC50 of 600 nM. |
| PC-21265 |
Feeblin
IRF5 inhibitor
|
Feeblin (SLC15A4 inhibitor C5) is a small molecule inhibitor of the proinflammatory TLR7/8/9-IRF5 pathway (IC50=1.6 uM) by disrupting the SLC15A4-TASL adapter module, Feeblin is an IRF5 pathway-specific inhibitor. |
| PC-21240 |
NOX-6-7
GPR132 agonist
|
NOX-6-7 is a potent, selective GPR132 agonist with EC50 of 44 nM. |
| PC-21239 |
NOX-6-18
GPR132 inhibitor
|
NOX-6-18 is a potent, selective GPR132 antagonist with IC50 of 17 nM. |
| PC-21213 |
YL-365
GPR34 inhibitor
|
YL-365 (YL365) is a highly potent, selective and competitive antagonist of GPR34. |
| PC-21184 |
UGT8 inhibitor 19
UGT8 inhibitor
|
UGT8 inhibitor 19 is a highly potent, selective and orally active ceramide galactosyltransferase enzyme UGT8 inhibitor with IC50 of 0.2 nM. |
| PC-21142 |
(3S) ALG-05
TILs inhibitor
|
(3S) ALG-05 is a potent pan-inhibitor of gut microbia tryptophan-indole-lyases (TILs, E.C. 4.1.99.1), exhibits inhibitory activity across TILs with Ki of 7-11 uM. |
| PC-21113 |
VJDT
TREM1 inhibitor
|
VJDT (TREM1 inhibitor) is a novel small molecule inhibitor of triggering receptor expressed on myeloid cell 1 (TREM1), effectively blocks TREM1 signaling. |
