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Cat. No. Product Name Information
PC-21744

G3BP inhibitor a

G3BP inhibitor

G3BP inhibitor a (G3Ia) is a specific, peptide mimetic inhibitor of RNA-binding proteins G3BP1/2 with SPR Kd value of 0.54 uM, blcoks the association of G3BP with its binding partners and inhibits condensation of G3BP both in vitro and in live cells.
PC-21741

GPR31 antagonist SAH2

GPR31 inhibitor

GPR31 antagonist SAH2 (SLU-0011371) is the first highly potent and selective small molecule GPR31 antagonist, antagonizes 12(S)-HETE-induced β-arrestin recruitment with IC50 of 1.09 uM.
PC-21724

L6H21

MD-2 inhibitor

L6H21 is an orally active, potent and specific myeloid differentiation 2 (MD-2) inhibitor with binding KD value of 33.3 uM, blocks the formation of the LPS-TLR4/MD-2 complex.
PC-21683

AJ2-30

SLC15A4 inhibitor

AJ2-30 is a specific small molecule SLC15A4 inhibitor with IFN-α suppression IC50 of 1.8  µM and MDP transport inhibition IC50 of 2.6  µM.
PC-21665

VY-3-249

ACSS2 inhibitor

VY-3-249 is a a potent Acetyl-CoA synthetase 2 (ACSS2) inhibitor with IC50 of 1.2 uM in in vitro biochemical TranScreener assays.
PC-21664

AD-8007

ACSS2 inhibitor

AD-8007 is a potent, brain permeable human Acetyl-CoA synthetase 2 (ACSS2) inhibitor with IC50 of 0.89 uM, a key metabolic enzyme involved in regulating fatty acid synthesis and protein acetylation in tumor cells.
PC-21663

AD-5584

ACSS2 inhibitor

AD-5584 is a potent, brain permeable human Acetyl-CoA synthetase 2 (ACSS2) inhibitor with IC50 of 0.86 uM, a key metabolic enzyme involved in regulating fatty acid synthesis and protein acetylation in tumor cells.
PC-21630

QP5038

QPCTL inhibitor

QP5038 is a potent inhibitor of glutaminyl-peptide cyclotransferase-like protein (QPCTL) with IC50 of 3.8 nM, shows promising in vitro and in vivo anti-tumor efficacies.
PC-21626

PQ912

Glutaminyl cyclase inhibitor

Varoglutamstat (PQ912) is a potent glutaminyl cyclase (QC) inhibitor with Ki values of 20-65 nM for human, rat, and mouse QC activity.
PC-21625

BK697

FIRΔexon2 inhibitor

BK697 is a small molecule targeting FIRΔexon2, potentially interacts with FIRΔexon2, significantly suppresses the FIRΔexon2 expression and inhibits tumor cell growth and several rRNA expressions.
PC-21576

PCC0105003

MARK inhibitor

PCC0105003 is a small molecule microtubule affinity-regulating kinases (MARKs) inhibitor with IC50 of 3.0, 2.0, 2.67 and 2.67 nM for MARK1, 2, 3 and 4 repectively.
PC-21575

BiTud

TDRD3 inhibitor

BiTud is a bivalent inhibitor against TDRD3 with binding Kd of 6 uM for tandem Tudor chimera, blocks the recruitment of TDRD3 by the two methylated arginines of G3BP1, suppress the phase separation of methylated G3BP1, TDRD3, and RNAs, and in turn inhibits the stress granule growth in cells.

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