UNC11676A

Chemical Structure : UNC11676A

Catalog No.: PC-26291Not For Human Use, Lab Use Only.

UNC11676A is a specific small molecule inhibitor of RNA helicase MDA5 with IC50 of 6 uM, >18-fold selective inhibition over LGP2 and DDX1.

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Biological Activity

UNC11676A is a specific small molecule inhibitor of RNA helicase MDA5 with IC50 of 6 uM, >18-fold selective inhibition over LGP2 and DDX1.

M.Wt	534.53
Formula	C23H17F3N4O4S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-Methoxy-4-((4'-methyl-2'-(2-(trifluoromethyl)benzamido)-[4,5'-bithiazol]-2-yl)amino)benzoic acid

1. Wang X, et al. Eur J Med Chem. 2026 Feb 26;309:118724.