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GALK1-IN-1

Chemical Structure : GALK1-IN-1

CAS No.: 669718-48-3

GALK1-IN-1

Catalog No.: PC-26467Not For Human Use, Lab Use Only.

GALK1-IN-1 is an effective ATP-competitive galactokinase 1 (GALK1) inhibitor with IC50 of 1 uM in luminescence GALK-ATP-depletion assay.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

GALK1-IN-1 is an effective ATP-competitive galactokinase 1 (GALK1) inhibitor with IC50 of 1 uM in luminescence GALK-ATP-depletion assay.

Physicochemical Properties

M.Wt 336.40
Formula C19H20N4O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2'-(Benzo[d]oxazol-2-ylamino)-7',8'-dihydro-3'H-spiro[cyclopentane-1,4'-quinazolin]-5'(6'H)-one

References

1. Sabrina R Mackinnon, et al. ACS Chem Biol. 2021 Apr 16;16(4):586-595.

2. Li Liu, et al. Bioorg Med Chem Lett. 2015 Feb 1;25(3):721-7.

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