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PON2 inhibitor 2

Chemical Structure : PON2 inhibitor 2

CAS No.: 887855-02-9

PON2 inhibitor 2

Catalog No.: PC-26445Not For Human Use, Lab Use Only.

PON2 inhibitor 2 is a potent, specific small molecule inhibitor of paraxonase 2 (PON2) with IC50 of 56 nM, inhibits the lactonase activity of PON2.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PON2 inhibitor 2 is a potent, specific small molecule inhibitor of paraxonase 2 (PON2) with IC50 of 56 nM, inhibits the lactonase activity of PON2.

Physicochemical Properties

M.Wt 377.51
Formula C22H23N3OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5,9-dimethyl-1-((3-(p-tolyloxy)propyl)thio)-[1,2,4]triazolo[4,3-a]quinoline

References

1. Bianconi E, et al. J Enzyme Inhib Med Chem. 2026 Dec;41(1):2643935.

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