Thiostrepton

Chemical Structure : Thiostrepton

CAS No.: 1393-48-2

Catalog No.: PC-26220Not For Human Use, Lab Use Only.

Thiostrepton is a thiazole antibiotic that selectively inhibits FOXM1, also significantly inhibits ETV4 K97-Khib, thereby promoting ferroptosis and suppressing ICC cell migration, invasion, and lung metastasis.

Packing	Price	Stock
100 mg	$58	In stock
250 mg	$88	In stock
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Biological Activity

Physicochemical Properties

M.Wt	1664.89
Formula	C72H85N19O18S5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-[(7R,8S)-2-Carboxy-7,8-dihydro-8-hydroxy-4-[(1S)-1-hydroxyethyl]-7-quinolinyl]-L-isoleucyl-L-alanyl-2,3-didehydroalanyl-L-alanyl-2-[(4aR,11S,14Z,18S,21S,28S,32aS)-4a-amino-21-[(1S,2R)-1,2-dihydroxy-1-methylpropyl]-14-ethylidene-3,4,4a,9,10,11,12,13,14,18,19,20,21,27,28,32a-hexadecahydro-11,28-bis[(1R)-1-hydroxyethyl]-9,12,19,26-tetraoxo-17H,26H-8,5:18,15:25,22:32,29-tetranitrilo-5H,15H-pyrido[3,2-m][1,11,17,24,4,7,20,27]tetrathiatetraazacyclotriacontin-2-yl]-4-thiazolecarbonyl-2,3-didehydroala

References

1. Ajaybabu V Pobbati, et al. Theranostics. 2020 Feb 18;10(8):3622-3635.

2. Xuan Zhang, et al. Oncotarget. 2014 Nov 30;5(22):11365-80.

Thiostrepton

Biological Activity

Physicochemical Properties

References

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