| Cat. No. |
Product Name |
Information |
| PC-23557 |
AJO14
NUPR1 inhibitor
|
AJO14 is a specific and effective NUPR1 inhibitor with Kd of 4.9 uM. |
| PC-23556 |
Purpurin
GDH1 inhibitor
|
Purpurin is a potent, specific inhibitor of glutamate dehydrogenase 1 (GDH1/GLUD1) with Ki of 1.9 uM, inhibits cancer cell proliferation and tumor growth. |
| PC-23555 |
R162
GDH1 inhibitor
|
R162 is a potent, specific inhibitor of glutamate dehydrogenase 1 (GDH1/GLUD1) with Ki of 28.6 uM, inhibits cancer cell proliferation and tumor growth. |
| PC-23544 |
LH1513
CaOx crystallization inhibitor
|
LH1513 (L-Lysine Dioxalate) is potent inhibitor of calcium oxalate (CaOx) crystallization with EC50 of 21.7 uM. |
| PC-23540 |
FPD5
Esterase D inhibitor
|
FPD5 is a small molecule activator of esterase D (ESD) with KD value of 0.8 nM, directly binds to ESD at Lys180 rather than its ubiquitination site Lys213. |
| PC-23538 |
WYFA15
SMS1 inhibitor
|
WYFA15 is a small molecule inhibitor of sphingomyelin synthase 1 (SMS1), inhibits severe fever with thrombocytopenia syndrome virus (SFTSV) infection and reduces SARS-CoV-2 replication and pathogenesis. |
| PC-23530 |
ROR1 inhibitor 19h
ROR1 inhibitor
|
ROR1 inhibitor 19h is a potent, specfic inhibitor of receptor tyrosine kinase-like orphan receptor 1 (ROR1) with SPR KD of 1.1 μM, exhibits antitumor activity in lung cancer and breast cancer cell lines (IC50: 0.36-1.37 μM). |
| PC-23529 |
ARI-1
ROR1 inhibitor
|
ARI-1 is a specific inhibitor of receptor tyrosine kinase-like orphan receptor 1 (ROR1), directly targets the frizzled domain with high binding affinity, inhibits EGFR-TKIs-resisted NSCLC with high ROR1 expression. |
| PC-23520 |
Warfarin
VKORC1L1 inhibitor
|
Warfarin (WARF-42, Athrombine-K) is a potent anticoagulant agent and a vitamin K1 recycling antagonist to deplete active vitamin K1, is a small molecular inhibitor of vitamin K epoxide reductase complex subunit 1 like 1 (VKORC1L1). |
| PC-23519 |
Necrocide-1
Necrosis inducer
|
Necrocide-1 (NC1) is a small molecule inducer of tumor necrosis factor (TNF)-independent necrosis, shows antiproliferative activity with IC50 values of 0.48 and 2 nM for MCF-7 and PC3, respectively |
| PC-23518 |
CNOT6L inhibitor iD1
CNOT6L inhibitor
|
CNOT6L inhibitor iD1 (Inhibitor of CNOT6L Deadenylase 1, ICCB-475) is a specific small molecule inhibitor of CCR4-NOT deadenylase subunit CNOT6L with Kd of 7.6 uM and IC50 of 2.5 uM in FRET-based deadenylase assay, modestly inhibits homolog CNOT6 and does not inhibit CNOT7 or CNOT8. |
| PC-23516 |
BC-DXI-843
AIMP2-DX2 inhibitor
|
BC-DXI-843 is a potent and specific AIMP2-DX2 inhibitor with IC50 og 0.92 uM, >100-fold selectivity over AIMP2. |
