| Cat. No. |
Product Name |
Information |
| PC-26585 |
FUBP1-IN-1
FUBP1 inhibitor
|
FUBP1-IN-1 is a small molecule inhibitor of transcriptional regulator FUSE binding protein 1 (FUBP1), inhibits the binding of FUBP1 to the FUSE sequence with IC50 of 11.0 uM, reduces cell expansion and induces of cell death in hepatocellular carcinoma cells. |
| PC-26574 |
Rnaseh2c-In1
Rnaseh2c inhibitor
|
Rnaseh2c-In1 is a specific small molecule inhibits of ribonuclease H2 subunit C (Rnaseh2c), significantly inhibits the proliferation of HCC via Cdk9 proliferation axis and CCL2/CCR2-mediated CD8+ Tex infiltration. |
| PC-26567 |
ELMO2 inhibitor C52
ELMO2 inhibitor
|
ELMO2 inhibitor C52 is a specific small-molecule Engulfment and cell motility 2 (ELMO2) inhibitor, binds to ELMO2 with a dissociation constant (KD) of 1.0 uM, effectively kills ELMO3-low lung cancer cells and EGFR inhibitor-resistant cells. |
| PC-26553 |
ZNF281 inhibitor ZIM
ZNF281 inhibitor
|
ZNF281 inhibitor ZIM (ZNF281 Interfering Molecule) is a specific small molecule inhibitor of transcription factor ZNF281, prevents anthracycline-mediated cardiotoxicity (AIC), enhances lung tumor regression, and prevents lung metastasis in a metastatic melanoma model. |
| PC-26552 |
BTdCPU
HRI activator
|
BTdCPU is a potent activator of heme-regulated inhibitor (HRI) eIF2α kinase that promotes eIF2α phosphorylation and induces apoptosis in Dexamethasone-resistant cancer cells. |
| PC-26548 |
SOD1 stabilizer C7
SOD1 binder
|
SOD1 stabilizer C7 is a SOD1-stabilizing small molecule preferentially bound the native-like conformation of SOD1, inhibits irreversible apo-SOD1 misfolding in vitro. |
| PC-26506 |
CCF0054500
OR2L13 agonist
|
CCF0054500 is a specific small molecule agonist of orphan GPCR OR2L13, inhibits inhibit platelet aggregation in platelet-rich plasma (PRP) with EC50 of 14 uM. |
| PC-26503 |
Z1149421873
NAP1L1 inhibitor
|
Z1149421873 (Z11) is a small-molecule inhibitor of NAP1L1 with SPR Kd value of 7.86 nM, inhibits its protein expression in vitro and exerts anti-fibrotic effects in PMCFs. |
| PC-26502 |
SARM1 inhibitor 19
SARM1 inhibitor
|
SARM1 inhibitor 19 is a potent, selective and orally bioavailable SARM1 inhibitor with pIC50 of 7.1 (hSARM1), protect primary rat and mouse DRGs treated with vincristine with EC50 of 55 nM and 113 nM respectively. |
| PC-26495 |
S-Nitroso-N-acetyl-DL-penicillamine
NO donor
|
S-Nitroso-N-acetyl-DL-penicillamine (SNAP) is a synthetic NO donor that releases NO under physiological conditions, acts as a stable inhibitor of platelet aggregation. |
| PC-26468 |
NCGC00238624
GALK1 inhibitor
|
NCGC00238624 is a highly selective galactokinase (GALK1) inhibitor with IC50 of 7.69 and 13.67 uM against the human and mouse recombinant GALK1, respectively, lowers gal-1P levels in primary fibroblast cells derived from patients with classic galactosemia. |
| PC-26467 |
GALK1-IN-1
GALK1 inhibitor
|
GALK1-IN-1 is an effective ATP-competitive galactokinase 1 (GALK1) inhibitor with IC50 of 1 uM in luminescence GALK-ATP-depletion assay. |
