Chemical Structure : Shz-1
CAS No.: 326886-05-9
Catalog No.: PC-70268Not For Human Use, Lab Use Only.
Shz-1 is a small cardiogenic molecule that potently induces Nkx2.5 and a subset of other cardiac markers, including myocardin, troponin-I, and sarcomeric α-tropomyosin (SαTM) in a variety of different stem/progenitor cells.
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Shz-1 is a small cardiogenic molecule that potently induces Nkx2.5 and a subset of other cardiac markers, including myocardin, troponin-I, and sarcomeric α-tropomyosin (SαTM) in a variety of different stem/progenitor cells.
Shz-1 triggers cardiac mRNA and protein expression in a variety of embryonic and adult stem/progenitor cells, including human mobilized peripheral blood mononuclear cells (M-PBMCs).
Shz-1 displays cardioregenerative activity as xenografts in injured immunocompromised rat heart.
M.Wt | 355.21 | |
Formula | C13H11BrN2O3S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
Benzenesulfonic acid, [(5-bromo-2-hydroxyphenyl)methylene]hydrazide (9CI) |
1. Sadek H, et al. Proc Natl Acad Sci U S A. 2008 Apr 22;105(16):6063-8.
2. Nan C, et al. Cardiovasc Toxicol. 2015 Jan;15(1):29-40.
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