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ML181

Chemical Structure : ML181

CAS No.: 1415356-28-3

ML181 (CYM50557)

Catalog No.: PC-38612Not For Human Use, Lab Use Only.

ML181 (CYM50557) is a potent and selective GPR7 (Neuropeptides B/W receptor 1, NPBW1) antagonist probe with IC50 of 270 nM for inhibition of NPW-induced GPR7 activation.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    ML181 (CYM50557) is a potent and selective GPR7 (Neuropeptides B/W receptor 1, NPBWR1) antagonist probe with IC50 of 270 nM for inhibition of NPW-induced GPR7 activation.

    Physicochemical Properties

    M.Wt 356.806
    Formula C19H17ClN2O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    5-Chloro-2-(3,5-dimethylphenyl)-4-(4-methoxyphenoxy)pyridazin-3-one

    References

    1. Mariangela Urbano, et al. Bioorg Med Chem Lett. 2012 Dec 1;22(23):7135-41.

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