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Chemical Structure : AL-GDa62
Catalog No.: PC-72537Not For Human Use, Lab Use Only.
AL-GDa62 is a specific inhibitor of TCOF1, ARPC5, and UBC9, inhibits SUMOylation at low micromolar concentrations.
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AL-GDa62 is a specific inhibitor of TCOF1, ARPC5, and UBC9, inhibits SUMOylation at low micromolar concentrations.
AL-GDa62 preferentially induced apoptosis in CDH1–/– cells, and Cdh1–/– mammary and gastric organoids were significantly more sensitive to AL-GDa62 at low micromolar concentrations.
AL-GDa62 is a potential synthetic lethal lead for the treatment of gastric cancer.
| M.Wt | 393.506 | |
| Formula | C24H28FN3O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Luxenburger A, et al. J Med Chem. 2021 Dec 23;64(24):18114-18142.
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