Chemical Structure : 5MPN
CAS No.: 47208-82-2
Catalog No.: PC-35343Not For Human Use, Lab Use Only.
PFKFB4 inhibitor 5MPN is a first-in-class, selective, competitive, orally available inhibitor of PFKFB4 with Ki of 8.6 uM, does not inhibit PFK-1 or PFKFB3.
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5 mg | $188 | In stock | |
10 mg | $298 | In stock | |
25 mg | $478 | In stock | |
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PFKFB4 inhibitor 5MPN is a first-in-class, selective, competitive, orally available inhibitor of PFKFB4 with Ki of 8.6 uM, does not inhibit PFK-1 or PFKFB3.
PFKFB4 inhibitor 5MPN suppresses the glycolysis and proliferation of multiple human cancer cell lines but not non-transformed epithelial cells in vitro.
PFKFB4 inhibitor 5MPN suppresses the glucose metabolism and growth of tumors in mice.
M.Wt | 305.334 | |
Formula | C15H19N3O4 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
5-(n-(8-methoxy-4-quinolyl)amino)pentyl nitrate |
1. Chesney J, et al. Oncotarget. 2015 Jul 20;6(20):18001-11.
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