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MrgX1 modulator 8e

Chemical Structure : MrgX1 modulator 8e

CAS No.: 2700254-51-7

MrgX1 modulator 8e

Catalog No.: PC-38501Not For Human Use, Lab Use Only.

MrgX1 inhibitor 8e is a potent, allosteric modulator of MrgX1 with EC50 of 13 nM, shows improved potency and microsomal stability than ML382.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    MrgX1 inhibitor 8e is a potent, allosteric modulator of MrgX1 with EC50 of 13 nM, shows improved potency and microsomal stability than ML382.

    Physicochemical Properties

    M.Wt 396.409
    Formula C18H18F2N2O4S
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    2-(cyclopropanesulfonamido)-N-(2-ethoxy-5-fluorophenyl)-5-fluorobenzamide

    References

    1. Swagat Sharma, et al. ACS Med. Chem. Lett. 2022.

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