Chemical Structure : OGT 2115
CAS No.: 853929-59-6
Catalog No.: PC-23394Not For Human Use, Lab Use Only.
OGT 2115 is a potent, specific, cell-permeable and orally active heparanase inhibitor with IC50 of 0.4 uM, inhibits the expression and activity of heparanase.
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|---|---|---|---|
| 5 mg | $78 | In stock | |
| 10 mg | $118 | In stock | |
| 25 mg | $218 | In stock | |
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OGT 2115 is a potent, specific, cell-permeable and orally active heparanase inhibitor with IC50 of 0.4 uM, inhibits the expression and activity of heparanase.
OGT 2115 decreases mitochondrial oxygen consumption, inhibited mitochondrial complex II-III activity.
OGT 2115 dramatically reduces HSV-2 release from vaginal epithelial cells.
OGT 2115 inhibits invasion and migration of breast cancer cells through the downregulation of heparanase.
| M.Wt | 495.30 | |
| Formula | C24H16BrFN2O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2-(2-(4-(3-(4-Bromophenyl)acrylamido)-3-fluorophenyl)benzo[d]oxazol-5-yl)acetic acid |
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1. Courtney SM, et al. Bioorg Med Chem Lett. 2005 May 2;15(9):2295-9.
2. Li Y, et al. Int J Mol Med. 2013 May;31(5):1234-42.

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