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Chemical Structure : HPA-12
CAS No.: 383418-30-2
Catalog No.: PC-23326Not For Human Use, Lab Use Only.
HPA-12 is a small molecule inhibitor of ceramide trafficking/ceramide transporter (CERT), inhibits sphingomyelin biosynthesis.
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| 5 mg | $428 | In stock | |
| 10 mg | $728 | In stock | |
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HPA-12 is a small molecule inhibitor of ceramide trafficking/ceramide transporter (CERT), inhibits sphingomyelin biosynthesis.
HPA-12 inhibits conversion of ceramide to SM, but not to glucosylceramide, in Chinese hamster ovary cells.
HPA-12 does not inhibit the activity of sphingomyelin (SM) synthase.
| M.Wt | 363.54 | |
| Formula | C22H37NO3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(1R,3R)-N-(3-hydroxy-1-hydroxymethyl-3-phenylpropyl)dodecanamide |
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1. Charruyer A, et al. J Biol Chem. 2008 Jun 13;283(24):16682-92.
2. Nakamura Y, et al. J Med Chem. 2003 Aug 14;46(17):3688-95.
3. Yasuda S, et al. J Biol Chem. 2001 Nov 23;276(47):43994-4002.
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