Chemical Structure : HPA-12
CAS No.:
383418-30-2
HPA-12
(HPA12)
Catalog No. : PC-23326Not For Human Use, Lab Use Only.
HPA-12 is a small molecule inhibitor of ceramide trafficking/ceramide transporter (CERT), inhibits sphingomyelin biosynthesis.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-2332601
Biological Activity
HPA-12 is a small molecule inhibitor of ceramide trafficking/ceramide transporter (CERT), inhibits sphingomyelin biosynthesis.
Physicochemical Properties
M.Wt
363.54
Formula
C22H37NO3
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
(1R,3R)-N-(3-hydroxy-1-hydroxymethyl-3-phenylpropyl)dodecanamide
References
1. Charruyer A, et al. J Biol Chem. 2008 Jun 13;283(24):16682-92.
2. Nakamura Y, et al. J Med Chem. 2003 Aug 14;46(17):3688-95.
3. Yasuda S, et al. J Biol Chem. 2001 Nov 23;276(47):43994-4002.
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