AA92593 | OPN4 antagonist | Probechem Biochemicals

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Chemical Structure : AA92593

CAS No.: 457961-34-1

AA92593 (AA 92593)

Catalog No.: PC-38201Not For Human Use, Lab Use Only.

AA92593 is a selective and competitive OPN4 (melanopsin) antagonist with IC50 of 665 nM.

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10 mg	$98	In stock
25 mg	$168	In stock
50 mg	$268	In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

AA92593 is a selective and competitive OPN4 (melanopsin) antagonist with IC50 of 665 nM.
AA92593 attenuated melanopsin photocurrent in a dose-dependent manner, inhibited melanopsin photoresponses without inhibiting rod/cone function.
AA92593 reversibly attenuated melanopsin-mediated photoresponses.

Physicochemical Properties

M.Wt	269.359
Formula	C13H19NO3S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-((4-methoxy-3-methylphenyl)sulfonyl)piperidine

References

1. Kenneth A Jones, et al. Nat Chem Biol. 2013 Oct;9(10):630-5.

2. Qiushi Wang, et al. Mol Cancer Res. 2020 Jul;18(7):1028-1038.

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AA92593 (AA 92593)

Biological Activity

Physicochemical Properties

References

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