Chemical Structure : AA92593
CAS No.: 457961-34-1
Catalog No.: PC-38201Not For Human Use, Lab Use Only.
AA92593 is a selective and competitive OPN4 (melanopsin) antagonist with IC50 of 665 nM.
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AA92593 is a selective and competitive OPN4 (melanopsin) antagonist with IC50 of 665 nM.
AA92593 attenuated melanopsin photocurrent in a dose-dependent manner, inhibited melanopsin photoresponses without inhibiting rod/cone function.
AA92593 reversibly attenuated melanopsin-mediated photoresponses.
M.Wt | 269.359 | |
Formula | C13H19NO3S | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
1-((4-methoxy-3-methylphenyl)sulfonyl)piperidine |
1. Kenneth A Jones, et al. Nat Chem Biol. 2013 Oct;9(10):630-5.
2. Qiushi Wang, et al. Mol Cancer Res. 2020 Jul;18(7):1028-1038.
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