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SCL-LMO2 inhibitor 3K7

Chemical Structure : SCL-LMO2 inhibitor 3K7

CAS No.: 2060405-72-1

SCL-LMO2 inhibitor 3K7

Catalog No.: PC-38158Not For Human Use, Lab Use Only.

SCL-LMO2 inhibitor 3K7 is a small molecule, specific inhibitor of the SCL-LMO2 PPI, binds directly to LMO2 with Kd of 1.2 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    SCL-LMO2 inhibitor 3K7 is a small molecule, specific inhibitor of the SCL-LMO2 PPI, binds directly to LMO2 with Kd of 1.2 uM.
    3K7 does not bind to the other 3 known members of the LMO family: LMO1, LMO3 and LMO4. 3K7 induces a change in LMO2 conformation.

    Physicochemical Properties

    M.Wt 447.579
    Formula C27H33N3O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (4-(3,5-dimethylphenyl)tetrahydro-2H-pyran-4-yl)(6-(imidazo[1,2-a]pyridin-6-ylmethyl)-1,4-oxazepan-4-yl)methanone

    References

    1. Leanne Milton-Harris, et al. Oncotarget. 2020 May 12;11(19):1737-1748.

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