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UNC5452

Chemical Structure : UNC5452

CAS No.: 943434-15-9

UNC5452 (UNC 5452)

Catalog No.: PC-47091Not For Human Use, Lab Use Only.

UNC5452 is a selective NIMA-related kinase 1 (Nek1) inhibitor with IC50 of 4.3 uM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

UNC5452 is a selective NIMA-related kinase 1 (Nek1) inhibitor with IC50 of 4.3 uM.

Physicochemical Properties

M.Wt 344.433
Formula C17H20N4O2S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(2-(dimethylamino)ethyl)-4-(1H-pyrrolo[2,3-b]pyridin-4-yl)benzenesulfonamide

References

1. Georg Baumann, et al. J Med Chem. 2022 Jan 27;65(2):1265-1282.

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