α-chlorofluoroacetamide | | Probechem Biochemicals

Chemical Structure : α-chlorofluoroacetamide

α-chlorofluoroacetamide (CFA)

Catalog No.: PC-22302Not For Human Use, Lab Use Only.

α-chlorofluoroacetamide (CFA) is a novel warhead of targeted covalent inhibitor (TCI), shows high reactivity toward Cys797 of epidermal growth factor receptor (EGFR).

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Biological Activity

α-chlorofluoroacetamide (CFA) is a novel warhead of targeted covalent inhibitor (TCI), shows high reactivity toward Cys797 of epidermal growth factor receptor (EGFR).

Physicochemical Properties

M.Wt	111.50
Formula	C2H3ClFNO
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	alpha-chlorofluoroacetamide

References

1. Naoya Shindo, et al. Nat Chem Biol. 2019 Mar;15(3):250-258.

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α-chlorofluoroacetamide (CFA)

Biological Activity

Physicochemical Properties

References

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