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α-chlorofluoroacetamide

Chemical Structure : α-chlorofluoroacetamide

CAS No.: 431-09-4

α-chlorofluoroacetamide (CFA)

Catalog No.: PC-22302Not For Human Use, Lab Use Only.

α-chlorofluoroacetamide (CFA) is a novel warhead of targeted covalent inhibitor (TCI), shows high reactivity toward Cys797 of epidermal growth factor receptor (EGFR).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

α-chlorofluoroacetamide (CFA) is a novel warhead of targeted covalent inhibitor (TCI), shows high reactivity toward Cys797 of epidermal growth factor receptor (EGFR).

Physicochemical Properties

M.Wt 111.50
Formula C2H3ClFNO
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

alpha-chlorofluoroacetamide

References

1. Naoya Shindo, et al. Nat Chem Biol. 2019 Mar;15(3):250-258.

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