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SC26196

Chemical Structure : SC26196

CAS No.: 218136-59-5

SC26196 (SC-26196)

Catalog No.: PC-22255Not For Human Use, Lab Use Only.

SC26196 (SC-26196) is a potent, selective delta6 desaturase (Δ6 desaturase, D6D, FADS2) inhibitor with IC50 of 0.2 uM in rat liver microsomal assay.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

SC26196 (SC-26196) is a potent, selective delta6 desaturase (Δ6 desaturase, D6D, FADS2) inhibitor with IC50 of 0.2 uM in rat liver microsomal assay.
SC26196 inhibits tumorigenesis in in vivo models of intestinal cancer.
SC26196 enhances radiation therapy in glioblastoma in vitro and in vivo.

Physicochemical Properties

M.Wt 423.56
Formula C27H29N5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2,2-Diphenyl-5-(4-((pyridin-3-ylmethylene)amino)piperazin-1-yl)pentanenitrile

References

1. Obukowicz MG, et al. J Pharmacol Exp Ther. 1998 Oct;287(1):157-66.

2. Hansen-Petrik MB, et al. Cancer Lett. 2002 Jan 25;175(2):157-63.

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