SC26196 | D6D inhibitor | Probechem Biochemicals

Chemical Structure : SC26196

CAS No.: 218136-59-5

SC26196 (SC-26196)

Catalog No.: PC-22255Not For Human Use, Lab Use Only.

SC26196 (SC-26196) is a potent, selective delta6 desaturase (Δ6 desaturase, D6D, FADS2) inhibitor with IC50 of 0.2 uM in rat liver microsomal assay.

Packing	Price	Stock
5 mg	$128	In stock
10 mg	$188	In stock
25 mg	$298	In stock
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Biological Activity

SC26196 (SC-26196) is a potent, selective delta6 desaturase (Δ6 desaturase, D6D, FADS2) inhibitor with IC50 of 0.2 uM in rat liver microsomal assay.
SC26196 inhibits tumorigenesis in in vivo models of intestinal cancer.
SC26196 enhances radiation therapy in glioblastoma in vitro and in vivo.

Physicochemical Properties

M.Wt	423.56
Formula	C27H29N5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2,2-Diphenyl-5-(4-((pyridin-3-ylmethylene)amino)piperazin-1-yl)pentanenitrile

References

1. Obukowicz MG, et al. J Pharmacol Exp Ther. 1998 Oct;287(1):157-66.

2. Hansen-Petrik MB, et al. Cancer Lett. 2002 Jan 25;175(2):157-63.

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SC26196 (SC-26196)

Biological Activity

Physicochemical Properties

References

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