Chemical Structure : Imifoplatin
Catalog No.: PC-25340Not For Human Use, Lab Use Only.
Imifoplatin (PT-112) is the first pyrophosphate-platinum conjugate, causes immunogenic cell death in experimental models, is an immunogenic cell death (ICD)-inducing small molecule, inhibits ribosome biogenesis and causes organelle stresses, leading to selective ICD in cancer cells.
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Imifoplatin (PT-112) is the first pyrophosphate-platinum conjugate, causes immunogenic cell death in experimental models, is an immunogenic cell death (ICD)-inducing small molecule, inhibits ribosome biogenesis and causes organelle stresses, leading to selective ICD in cancer cells.
M.Wt | 485.23 | |
Formula | C6H16N2O7P2Pt | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Yamazaki T, et al. Oncoimmunology. 2020 Feb 11;9(1):1721810.
2. Karp DD, et al. EClinicalMedicine. 2022 May 27;49:101430.
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