BC8a | hClpP inhibitor | Probechem Biochemicals

Chemical Structure : BC8a

Catalog No.: PC-25347Not For Human Use, Lab Use Only.

BC8a (ClpP inhibitor 8a) is a potent inhibitor of hClpP with IC50 of 10.2 uM, inhibits hClpP peptidase activity, also inhibits the holoenzyme hClpXP.

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Biological Activity

BC8a (ClpP inhibitor 8a) is a potent inhibitor of hClpP with IC50 of 10.2 uM, inhibits hClpP peptidase activity, also inhibits the holoenzyme hClpXP.

M.Wt	412.72
Formula	C19H30BClN2O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	((R)-1-((S)-2-(2-Chloro-4-methoxybenzamido)-4-methylpentanamido)-3-methylbutyl)boronic Acid

1. Tan J, et al. J Med Chem. 2019 Jul 11;62(13):6377-6390.

2. Barghash MM, et al. Structure. 2025 Aug 5:S0969-2126(25)00261-8.