PRDX1 inhibitor CP1

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Chemical Structure : PRDX1 inhibitor CP1

Catalog No.: PC-25317Not For Human Use, Lab Use Only.

PRDX1 inhibitor CP1 is a potent, high-affinity small molecule peroxiredoxin 1 (PRDX1) inhibitor with IC50 of 0.08 nM and MST binding Kd of 0.06 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

PRDX1 inhibitor CP1 is a potent, high-affinity small molecule peroxiredoxin 1 (PRDX1) inhibitor with IC50 of 0.08 nM and MST binding Kd of 0.06 nM.
CP1 exhibits significant antiproliferative effects on A549, HepG2 and MCF-7 tumor cells without toxicity to other normal cells.

Physicochemical Properties

M.Wt	806.01
Formula	C48H59N3O8
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(6bS,8aS,11R,12aR,12bS,14aR)-11-(((3,5-dimethyl-6-(1,2,2-trihydroxyethyl)pyrazin-2-yl)methyl)carbamoyl)-4,6b,8a,11,12b,14a-hexamethyl-2-oxo-2,6b,7,8,8a,9,10,11,12,12a,12b,13,14,14a-tetradecahydropicen-3-yl (E)-3-(3-(hydroxymethyl)phenyl)acrylate

References

1. Guan L, et al. Front Pharmacol. 2025 Jul 23;16:1625604.

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