CSE inhibitor 43

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Chemical Structure : CSE inhibitor 43

Catalog No.: PC-72154Not For Human Use, Lab Use Only.

CSE inhibitor 43 is a novel potent, selective, competitive inhibitor of cystathionine γ-lyase (CSE) inhibitor with IC50 of 1.2 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

CSE inhibitor 43 is a novel potent, selective, competitive inhibitor of cystathionine γ-lyase (CSE) inhibitor with IC50 of 1.2 uM.
CSE inhibitor 43 displays high selectivity versus cystathionine β-synthase (CBS, >400-fold selectivity over).
CSE inhibitor 43 is potentially valuable pharmacological tool for the study of H2S signaling.

Physicochemical Properties

M.Wt	378.44
Formula	C16H15FN4O2S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((4-methoxyphenyl)amino)-2-oxoethyl (E)-2-((3-fluoropyridin-2-yl)methylene)hydrazine-1-carbodithioate

References

1. Bhattacharjee A, ACS Med Chem Lett. 2017 Nov 21;8(12):1241-1245.

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CSE inhibitor 43

Biological Activity

Physicochemical Properties

References

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