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CSE inhibitor 43

Chemical Structure : CSE inhibitor 43

CAS No.: 2190517-61-2

CSE inhibitor 43

Catalog No.: PC-72154Not For Human Use, Lab Use Only.

CSE inhibitor 43 is a novel potent, selective, competitive inhibitor of cystathionine γ-lyase (CSE) inhibitor with IC50 of 1.2 uM.

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    Biological Activity

    CSE inhibitor 43 is a novel potent, selective, competitive inhibitor of cystathionine γ-lyase (CSE) inhibitor with IC50 of 1.2 uM.
    CSE inhibitor 43 displays high selectivity versus cystathionine β-synthase (CBS, >400-fold selectivity over).
    CSE inhibitor 43 is potentially valuable pharmacological tool for the study of H2S signaling.

    Physicochemical Properties

    M.Wt 378.44
    Formula C16H15FN4O2S2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20°C 12 Months; 4°C 6 Months
    In Solvent
    -80°C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    2-((4-methoxyphenyl)amino)-2-oxoethyl (E)-2-((3-fluoropyridin-2-yl)methylene)hydrazine-1-carbodithioate

    References

    1. Bhattacharjee A, ACS Med Chem Lett. 2017 Nov 21;8(12):1241-1245.

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