ZST316 |CAS:1816973-32-6 Probechem Biochemicals

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Chemical Structure : ZST316

ZST316 (ZST-316;ZST 316)

Catalog No.: PC-36013Not For Human Use, Lab Use Only.

ZST316 (ZST-316) is a small molecule DDAH1 (Dimethylarginine dimethylaminohydrolase 1) inhibitor with IC50 of 3 uM, Ki of 1 uM.

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Biological Activity

ZST316 (ZST-316) is a small molecule DDAH1 (Dimethylarginine dimethylaminohydrolase 1) inhibitor with IC50 of 3 uM, Ki of 1 uM.
ZST316 significantly attenuates formation of capillary-like tube structures in a dose-dependent fashion.
ZST316 significantly attenuates triple negative breast cancer cell vasculogenic mimicry in vitro.

Physicochemical Properties

M.Wt	309.385
Formula	309.385
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-2-amino-5-(3-(2-methoxyethyl)guanidino)-N-(methylsulfonyl)pentanamide

References

1. Hulin JA, et al. Biomed Pharmacother. 2019 Jan 3;111:602-612.

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ZST316 (ZST-316;ZST 316)

Biological Activity

Physicochemical Properties

References

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