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ML377

Chemical Structure : ML377

CAS No.: 2650088-70-1

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ML377 (MLS-0472732)

Catalog No.: PC-62119Not For Human Use, Lab Use Only.

ML377 (MLS-0472732) is a small molecule probe that selectively inhibits TAG (Triacylglyceride) accumulation with an IC50 of 1.1 uM, show >45-fold selectivity versus DGAT inhibition and cytotoxicity.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    ML377 (MLS-0472732) is a small molecule probe that selectively inhibits TAG (Triacylglyceride) accumulation with an IC50 of 1.1 uM, show >45-fold selectivity versus DGAT inhibition and cytotoxicity.

    Physicochemical Properties

    M.Wt 440.503
    Formula C26H24N4O3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    N-(3-(1H-benzo[d]imidazol-2-yl)phenyl)-2-(2-ethoxyethyl)-3-oxoiso-indoline-4-carboxamide

    References

    1. Hershberger PM, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].

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