ML377 (MLS-0472732) |CAS: 2650088-70-1 Probechem Biochemicals

Chemical Structure : ML377

ML377 (MLS-0472732)

Catalog No.: PC-62119Not For Human Use, Lab Use Only.

ML377 (MLS-0472732) is a small molecule probe that selectively inhibits TAG (Triacylglyceride) accumulation with an IC50 of 1.1 uM, show >45-fold selectivity versus DGAT inhibition and cytotoxicity.

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Biological Activity

ML377 (MLS-0472732) is a small molecule probe that selectively inhibits TAG (Triacylglyceride) accumulation with an IC50 of 1.1 uM, show >45-fold selectivity versus DGAT inhibition and cytotoxicity.

Physicochemical Properties

M.Wt	440.503
Formula	C26H24N4O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(3-(1H-benzo[d]imidazol-2-yl)phenyl)-2-(2-ethoxyethyl)-3-oxoiso-indoline-4-carboxamide

References

1. Hershberger PM, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].

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