OR51E2 antagonist C80 | OR51E2 inhibitor

Chemical Structure : OR51E2 antagonist C80

OR51E2 antagonist C80 (Compound 80)

Catalog No.: PC-22324Not For Human Use, Lab Use Only.

OR51E2 antagonist C80 (Compound 80) is an allosteric antagonist and inverse agonist of olfactory receptor OR51E2 with IC50 of 5.2 uM, acts as a negative allosteric modulator (NAM) by significantly decreasing the agonist efficacy.

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Biological Activity

Physicochemical Properties

M.Wt	447.77
Formula	C15H9ClF3N5O4S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-chloro-3-nitro-N-(4-(5-(trifluoromethyl)-1H-1,2,3-triazol-1-yl)phenyl)benzenesulfonamide

References

1. Tatjana Abaffy, et al. Mol Pharmacol. 2024 May 6:MOLPHARM-AR-2023-000843.

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OR51E2 antagonist C80 (Compound 80)

Biological Activity

Physicochemical Properties

References

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