Chemical Structure : GO-Y078
CAS No.: 1217503-60-0
Catalog No.: PC-38722Not For Human Use, Lab Use Only.
GO‐Y078 is a curcumin analog that suppresses angiogenesis through the inhibition of actin stress fiber formation, inhibits human umbilical venous epithelial cells resistant to angiogenesis inhibitors (HUVEC‐R) at 0.75 uM.
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GO‐Y078 is a curcumin analog that suppresses angiogenesis through the inhibition of actin stress fiber formation, inhibits human umbilical venous epithelial cells resistant to angiogenesis inhibitors (HUVEC‐R) at 0.75 uM.
GO‐Y078 decreases fibronectin 1 (FN1) gene expression.
GO‐Y078 inhibits angiogenesis through other pathways besides the VEGF pathway.
M.Wt | 400.427 | |
Formula | C22H24O7 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(1E,4E)-1-(4-Hydroxy-3,5-dimethoxyphenyl)-5-(3,4,5-trimethoxyphenyl)-1,4-pentadiene-3-one |
1. Kazuhiro Shimazu, et al. Cancer Sci. 2018 Oct;109(10):3285-3293.
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