Eptifibatide | Glycoprotein IIb/IIIa inhibitor

Chemical Structure : Eptifibatide

CAS No.: 188627-80-7

Eptifibatide (Integrilin)

Catalog No.: PC-73151Not For Human Use, Lab Use Only.

Eptifibatide (Integrilin) is a synthetic homodetic cyclic peptide, inhibits platelet aggregation by selectively blocking the platelet glycoprotein IIb/IIIa receptor.

Packing	Price	Stock
10 mg	$88	In stock
25 mg	$158	In stock
50 mg	$258	In stock
100 mg	$398	In stock
250 mg		Get quote

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Biological Activity

Eptifibatide (Integrilin) is a synthetic homodetic cyclic peptide, inhibits platelet aggregation by selectively blocking the platelet glycoprotein IIb/IIIa receptor.
Eptifibatide prevents the binding of fibrinogen, von Willebrand factor, and other adhesive ligands to platelet glycoprotein IIb/IIIa receptor.
Eptifibatide has a role as a platelet aggregation inhibitor and an anticoagulant.
Eptifibatide also binds to SARS-CoV-2 binding motifs of ACE2 receptor.

Physicochemical Properties

M.Wt	832.0
Formula	C35H49N11O9S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((3R,11S,17S,20S,25aS)-20-((1H-Indol-3-yl)methyl)-3-carbamoyl-11-(4-guanidinobutyl)-1,9,12,15,18,21-hexaoxodocosahydro-1H-pyrrolo[2,1-g][1,2,5,8,11,14,17,20]dithiahexaazacyclotricosin-17-yl)acetic acid

References

1. Furman MI, et al. J Am Coll Cardiol. 2004 Jun 16;43(12):2319-25.

2. Shweta Choudhary, et al. Front Immunol. 2020 Jul 10;11:1664.

Eptifibatide (Integrilin)

Biological Activity

Physicochemical Properties

References

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