Eptifibatide acetate

Chemical Structure : Eptifibatide acetate

CAS No.: 148031-34-9

Catalog No.: PC-73150Not For Human Use, Lab Use Only.

Eptifibatide acetate is a synthetic homodetic cyclic peptide, inhibits platelet aggregation by selectively blocking the platelet glycoprotein IIb/IIIa receptor.

Packing	Price	Stock
25 mg	$158	In stock
100 mg	$428	In stock
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1 g		Get quote

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Biological Activity

Eptifibatide acetate is a synthetic homodetic cyclic peptide, inhibits platelet aggregation by selectively blocking the platelet glycoprotein IIb/IIIa receptor.
Eptifibatide prevents the binding of fibrinogen, von Willebrand factor, and other adhesive ligands to platelet glycoprotein IIb/IIIa receptor.
Eptifibatide has a role as a platelet aggregation inhibitor and an anticoagulant.
Eptifibatide also binds to SARS-CoV-2 binding motifs of ACE2 receptor.

Physicochemical Properties

M.Wt	845.9
Formula	C35H49N11O9S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2-((3R,11S,17S,20S,25aS)-20-((1H-Indol-3-yl)methyl)-3-carbamoyl-11-(4-guanidinobutyl)-1,9,12,15,18,21-hexaoxodocosahydro-1H-pyrrolo[2,1-g][1,2,5,8,11,14,17,20]dithiahexaazacyclotricosin-17-yl)acetic acid acetate

References

1. Furman MI, et al. J Am Coll Cardiol. 2004 Jun 16;43(12):2319-25.

2. Shweta Choudhary, et al. Front Immunol. 2020 Jul 10;11:1664.