Catalog No.: PC-73149Not For Human Use, Lab Use Only.
DLin-MC3-DMA is an ionizable amino lipid (apparent pKa = 6.44) that has been used in combination with other lipids in the formation of lipid nanoparticles.
DLin-MC3-DMA is an ionizable amino lipid (apparent pKa = 6.44) that has been used in combination with other lipids in the formation of lipid nanoparticles.
Administration of Factor VII siRNA in DLin-MC3-DMA-containing lipid nanoparticles reduces plasma Factor VII protein levels in mice.
Formulations containing DLin-MC3-DMA have been used in the development of lipid nanoparticles for siRNA delivery in patients with hereditary transthyretin-mediated amyloidosis.
